[Metastatic process and therapies].

Michel Crépin
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Abstract

Tumor progression is now relatively well understood with changes at cellular and molecular levels. However mechanisms of the metastatic process are still not well elucidated. Several important questions remain unsolved to established new therapies. Moreover we need experimental animal models mimicking human metastatic disease to investigate and discover new targets for future therapies. These experimental approaches have to be coupled with pathological and clinical researches. Different experts will present the state of our knowledge in this domain.

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[转移过程和治疗方法]。
肿瘤的进展现在在细胞和分子水平的变化相对较好地理解。然而,转移过程的机制仍未得到很好的阐明。对于已建立的新疗法,有几个重要的问题仍未解决。此外,我们需要模拟人类转移性疾病的实验动物模型来研究和发现未来治疗的新靶点。这些实验方法必须与病理和临床研究相结合。不同的专家将介绍我们在这一领域的知识状况。
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