Breast-conserving treatment of breast cancer--oncological and reconstructive aspects.

Gynakologisch-geburtshilfliche Rundschau Pub Date : 2008-01-01 Epub Date: 2008-04-16 DOI:10.1159/000118932
Stefan Kramer, Maren Darsow, Sherko Kummel, Rainer Kimmig, Mahdi Rezai
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引用次数: 27

Abstract

Breast-conserving surgery combined with radiotherapy has become the treatment of choice for the majority of women presenting with primary breast cancer over the last 20 years. The extent of local excision remains a controversial issue in breast-conserving surgery. The wider the margins of clearance, the lower the risk of incomplete excision and thus of local recurrences, but the greater the amount of tissue removed, the higher the risk of visible deformity leading to an unacceptable cosmetic result. This clash of interests is most evident when attempting breast-conserving surgery in patients with smaller breast-tumor ratios. The widespread popularity of breast-conserving surgery has focused attention on new oncoplastic techniques that can avoid unacceptable cosmetic results. Partial mastectomy defects can be reconstructed by volume displacement, recruiting and transposing local glandular or dermoglandular flaps into the resection site, or by volume replacement, importing volume from elsewhere to replace the amount of tissue resected.

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乳腺癌保乳治疗——肿瘤学和重建方面。
在过去的20年里,保乳手术联合放疗已成为大多数原发性乳腺癌患者的治疗选择。局部切除的程度在保乳手术中仍然是一个有争议的问题。清除的边缘越宽,不完全切除和局部复发的风险越低,但切除的组织量越大,可见畸形的风险就越高,从而导致不可接受的美容结果。这种利益冲突在试图对乳房肿瘤比例较小的患者进行保乳手术时最为明显。乳房保乳手术的广泛流行使人们关注新的肿瘤整形技术,这些技术可以避免令人无法接受的美容结果。乳房部分切除后的缺损可以通过体积置换,将局部腺体或真皮腺瓣重新招募和转置到切除部位,或通过体积置换,从其他地方引入体积来替代切除的组织。
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