Synthesis, properties and biological activity of organotitanium substituted heteropolytungstates.

X Wang, J Li, J He, J Liu
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引用次数: 10

Abstract

Six new compounds [(CpTi)X, Cp=upsilon(nabla)-c(nabla)H(nabla), X=Ge, Ga, B) have been prepared and their Keggin structures determined by elementary analysis, IR, UV, (infinity)H NMR and (infinity for all)WNMR spectrometry. The results show that the complexes retain Keggin structure. The complexes exhibit antitumoral activity in vitro as shown by MTT experiment.

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有机钛取代杂多钨酸盐的合成、性质及生物活性。
合成了6个新化合物[(CpTi)X, Cp=upsilon(nabla)-c(nabla)H(nabla), X=Ge, Ga, B],并通过元素分析,IR, UV,(无穷远)H NMR和(无穷远)WNMR谱测定了它们的Keggin结构。结果表明,该配合物保持Keggin结构。MTT实验表明,该复合物具有体外抗肿瘤活性。
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