Disparities in cancer mortality among Alaska Native people, 1994-2003.

Alaska medicine Pub Date : 2008-01-01
Anne P Lanier, Gretchen Ehrsam Day, Janet J Kelly, Ellen Provost
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Abstract

Objective: To provide current data on cancer mortality among Alaska Native people for the period of 1994-2003, and to identify and quantitate cancer disparities.

Methods: Cancer mortality rates for Alaska Native (AN), U.S., White (USW) and other populations were calculated using SEERStat. Ratios of age-adjusted incidence rates with 95% confidence intervals are provided.

Results: Data were from SEERStat. Age-adjusted cancern mortality rates for Alaska Native exceeded those of USW population by 20%. For specific cancer sites, rates were significantly higher among AN people: oral cavity and pharynx (RR=1.9), esophagus (RR=2.0), stomach (RR=3.9), colon and rectum (RR=1.8), liver (RR=1.9), gallbladder (RR=2.6), pancreas (RR=1.3), lung and bronchus (RR=1.2), and kidney and renal pelvis (RR=2.2). In contrast, mortality rates among AN people were significantly lower than USW rates for cancers of the prostate (RR=0.7), brain and nervous system (RR=0.3), lymphoma (RR=0.6), and leukemia (RR=0.4).

Conclusion: Marked disparities in cancer mortality exist among the Alaska Native population compared to the US White population. Excess mortality is documented for all sites combined and for many cancer specific sites. Rates for all cancers combined and for select sites are among the highest of any racial/ethnic group in the United States.

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1994-2003年阿拉斯加原住民癌症死亡率的差异。
目的:提供1994-2003年阿拉斯加原住民癌症死亡率的最新数据,并确定和量化癌症差异。方法:使用SEERStat计算阿拉斯加原住民(AN)、美国人(us)、白人(USW)和其他人群的癌症死亡率。提供了年龄校正发病率的比值,置信区间为95%。结果:数据来源于SEERStat。阿拉斯加原住民年龄调整后的癌症死亡率比USW人口高20%。对于特定的癌症部位,AN人群的发病率明显更高:口腔和咽部(RR=1.9)、食道(RR=2.0)、胃(RR=3.9)、结肠和直肠(RR=1.8)、肝脏(RR=1.9)、胆囊(RR=2.6)、胰腺(RR=1.3)、肺和支气管(RR=1.2)、肾脏和肾盂(RR=2.2)。相比之下,AN人群的死亡率在前列腺癌(RR=0.7)、脑和神经系统癌(RR=0.3)、淋巴瘤(RR=0.6)和白血病(RR=0.4)方面明显低于USW。结论:与美国白人相比,阿拉斯加原住民的癌症死亡率存在显著差异。所有癌症部位和许多特定癌症部位的死亡率都有记录。所有癌症的综合发病率和特定部位的发病率是美国所有种族/族裔群体中最高的。
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