The implications of genetic susceptibility for the prevention of colorectal cancer: a qualitative study of older adults' understanding.

Community genetics Pub Date : 2008-01-01 Epub Date: 2008-05-20 DOI:10.1159/000121399
Jayne Lucke, Wayne Hall, Bree Ryan, Neville Owen
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引用次数: 13

Abstract

Objective: To assess whether public understandings of inherited predisposition to colorectal cancer may undermine preparedness to respond to preventive messages.

Methods: Structured in-depth interviews with 31 women and men, aged 50 years and over.

Results: Most participants viewed genetic factors as prompts for taking preventive measures rather than as reasons for fatalism and inaction. They were optimistic about the potential benefits of new developments in cancer prevention and treatment.

Conclusions: There was little evidence of perceived genetic determinism in relation to colorectal cancer, but there were some significant misunderstandings about causes, prevention and treatment. These findings have important implications for public health communications about the contribution of genetics to cancer causation.

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遗传易感性对预防结直肠癌的影响:老年人认识的定性研究。
目的:评估公众对结直肠癌遗传易感性的认识是否会影响对预防信息的响应。方法:对31名年龄在50岁及以上的男女进行结构化深度访谈。结果:大多数参与者将遗传因素视为采取预防措施的提示,而不是宿命论和无所作为的原因。他们对癌症预防和治疗新进展的潜在益处持乐观态度。结论:目前很少有证据表明基因决定论与结直肠癌有关,但在病因、预防和治疗方面存在一些明显的误解。这些发现对公共卫生宣传遗传学对癌症致病的影响具有重要意义。
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