The rabies situation in Far East Asia.

Developments in biologicals Pub Date : 2008-01-01
Z F Fu
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Abstract

This study evaluated rabies epidemiology in Far EastAsia. Questionnaires were sent by the OIE to Far East Asian countries and eight questionnaires were returned. Data were collected from these returns, as well as from recent publications, to gather information regarding rabies epidemiology in these countries. More than 29,000 human deaths were reported in 2006 in Far East Asia, representing more than 50% of all human rabies cases around the globe. There are only a few countries or regions from which no human rabies was reported in 2006 such as Japan, Singapore, South Korea, Malaysia, Hong Kong, and Taiwan. In many of these rabies endemic countries, the number of human rabies cases has not changed much during the past decade. The only country with a steady decline is Thailand, where the number of cases has decreased from around 200 to about 20 cases per year. The most dramatic changes were observed in China. Human rabies cases declined from around 5,000 cases per year in the 1980s to about 160 in the mid-1990s. However, these trends have since been reversed. A steady increase has been reported over the past 10 years with more than 3,200 cases reported in 2006. Although there are many factors that contribute to the epidemic or endemic nature of rabies in these countries, the single most important factor is the failure to immunize domestic dogs, which transmit rabies to humans. Dog vaccination is at or below 5% in many of these countries, and cannot stop the transmission of rabies from dogs to dogs, thus to humans. It is thus most importantforthese countries to initiate mass vaccination campaigns in dog populations in order to stop the occurrence of human rabies in Far East Asia.

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远东地区的狂犬病情况。
本研究评价了远东地区狂犬病流行病学。世界动物卫生组织向远东国家发送了调查问卷,并收回了8份调查问卷。从这些报告以及最近的出版物中收集数据,以收集有关这些国家狂犬病流行病学的信息。2006年,远东地区报告了29,000多人死亡,占全球所有人类狂犬病病例的50%以上。2006年只有日本、新加坡、韩国、马来西亚、香港和台湾等少数国家或地区未报告人类狂犬病病例。在许多这些狂犬病流行国家,人类狂犬病病例数在过去十年中没有太大变化。唯一稳步下降的国家是泰国,其病例数已从每年约200例减少到约20例。最显著的变化发生在中国。人类狂犬病病例由1980年代的每年约5,000例下降至1990年代中期的每年约160例。然而,这些趋势已经逆转。据报告,在过去10年里,病例稳步增加,2006年报告的病例超过3200例。虽然造成这些国家狂犬病流行或地方性的因素有很多,但最重要的一个因素是未能对可将狂犬病传播给人类的家养狗进行免疫接种。在这些国家中,许多国家的犬类疫苗接种率为5%或低于5%,无法阻止狂犬病从犬类传播到犬类,从而传播到人类。因此,对这些国家来说,最重要的是在犬群中开展大规模疫苗接种运动,以阻止远东地区人类狂犬病的发生。
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