The effect of high-dose topical corticosteroid therapy on prevention of recurrent nasal polyps after revision endoscopic sinus surgery.

American journal of rhinology Pub Date : 2008-09-01 Epub Date: 2008-08-04 DOI:10.2500/ajr.2008.22.3207

Il Gyu Kang, Byung Ki Yoon, Joo Hyun Jung, Heung Eog Cha, Seon Tae Kim

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引用次数: 38

Abstract

Background: Topical corticosteroid spray is widely used after endoscopic sinus surgery (ESS) to reduce the recurrence of polyposis. However, it has not always shown satisfactory results in clinical practice. We compared the effects of topical spray and high-dose topical steroid gauze packing on the prevention of recurrent nasal polyps after ESS.

Methods: We selected 32 patients with recurrent nasal polyps after ESS. In group 1, 18 patients were treated with topical steroid spray and in group 2, 14 patients were treated with triamcinolone acetonide-soaked (40 mg) gauze packing once a week for 2 months after revision ESS. We observed the recurrence of polyps between the two groups for 12 months.

Results: Polyps recurred in 8 of 18 patients in group 1 compared with 1 of 14 patients in group 2 (p = 0.044).

Conclusion: High-dose topical corticosteroid therapy may be more effective than low-dose topical therapy in preventing recurrent nasal polyps.

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大剂量外用皮质类固醇治疗对内镜鼻窦翻修术后复发性鼻息肉的预防作用。

背景:局部皮质类固醇喷雾剂被广泛应用于内镜鼻窦手术(ESS)后，以减少息肉病的复发。然而，在临床实践中并不总是显示出令人满意的结果。我们比较了外用喷雾剂和大剂量外用类固醇纱布填塞对ESS术后鼻息肉复发的预防作用。方法:选择32例ESS术后复发性鼻息肉患者。1组18例患者外用类固醇喷雾治疗，2组14例患者使用曲安奈德浸渍(40 mg)纱布包装，每周1次，持续2个月。观察两组息肉复发率12个月。结果:1组18例患者息肉复发8例，2组14例患者息肉复发1例(p = 0.044)。结论:大剂量外用皮质类固醇治疗可有效预防鼻息肉复发。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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American journal of rhinology

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