Evaluation of quality of life and psychological response in cancer patients treated with radiotherapy.

Radiation medicine Pub Date : 2008-08-01 Epub Date: 2008-09-04 DOI:10.1007/s11604-008-0248-5
Takeo Takahashi, Mikito Hondo, Keiichiro Nishimura, Akira Kitani, Takafumi Yamano, Hisami Yanagita, Hisato Osada, Munefumi Shinbo, Norinari Honda
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引用次数: 76

Abstract

Purpose: The importance of the quality of life (QOL) and mental condition of patients being treated for cancer is now recognized. In this study, we evaluated QOL and mental condition in patients with cancer before and after radiotherapy.

Materials and methods: The subjects were 170 patients who had undergone radiotherapy. The examination of QOL was performed using the quality of life questionnaire for cancer patients treated with anticancer drugs (QOL-ACD), and mental condition (anxiety and depression) was examined using the hospital anxiety and depression scale (HADS). These examinations were performed at the start of radiotherapy and immediately after radiotherapy.

Results: The QOL score was slightly higher in all patients after the completion of radiotherapy than before the start of radiotherapy. In the palliative radiotherapy group, QOL score was significantly improved by treatment. Anxiety and depression were improved after radiotherapy. There was a correlation between the degrees of improvement of the HADS and QOL score.

Conclusion: We could treat cancer patients by radiotherapy without reducing their QOL, and improvement in QOL was significant in the palliative radiotherapy group. Mental condition was also improved after radiotherapy.

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肿瘤放疗患者生活质量及心理反应的评价。
目的:癌症患者的生活质量(QOL)和精神状态的重要性已被认识到。在这项研究中,我们评估癌症患者放疗前后的生活质量和精神状况。材料与方法:以170例放疗患者为研究对象。采用接受抗癌药物治疗的癌症患者生活质量问卷(QOL- acd)对患者的生活质量进行检测,采用医院焦虑抑郁量表(HADS)对患者的精神状态(焦虑和抑郁)进行检测。这些检查在放疗开始时和放疗后立即进行。结果:放疗结束后所有患者的生活质量评分均略高于放疗前。姑息性放疗组经治疗后生活质量评分明显提高。放疗后焦虑、抑郁均有改善。HADS的改善程度与生活质量评分存在相关性。结论:姑息性放疗组对肿瘤患者的生活质量有明显的改善,且不降低患者的生活质量。放疗后精神状况也有所改善。
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