[Autoimmune pancreatitis. Related to a case].

A Villalobos Sánchez, A Muñoz Morente, I Pérez de Pedro, A Navarro Piñero, J M Reguera Iglesias, R Gómez Huelgas
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Abstract

Autoimmune pancreatitis is an entity that has recently been included in the differential diagnosis of chronic pancreatitis-pancreatic mass. The presence of diffuse, irregular Wirsung's duct stenosis, together with high levels of IgG4, the existence of certain autoantibodies and lymphoplasmacytic infiltration of the pancreas are key factors in the diagnosis. An early diagnostic suspicion and multidisciplinary collaboration are vital in these cases to avoid unnecessary surgery as the differential diagnosis is established with such entities as pancreas cancer, chronic pancreatitis, primary biliary cirrhosis or primary sclerosing cholangitis. Autoimmune pancreatitis has an excellent response to steroid therapy, with complete resolution of clinical, analytical and radiological parameters, as occurred in our patient. The very few cases reported so far suggest the need for the elaboration of long-term follow-up studies to determine the prognosis and frequency of its association with other diseases.

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自身免疫性胰腺炎。与案件有关]。
自身免疫性胰腺炎是最近被纳入慢性胰腺炎-胰腺肿块鉴别诊断的一个实体。弥漫性不规则Wirsung管狭窄,IgG4水平高,存在某些自身抗体和胰腺淋巴浆细胞浸润是诊断的关键因素。在这些病例中,早期诊断怀疑和多学科合作是至关重要的,以避免不必要的手术,因为胰腺癌、慢性胰腺炎、原发性胆汁性肝硬化或原发性硬化性胆管炎等实体已建立鉴别诊断。自身免疫性胰腺炎对类固醇治疗有很好的反应,临床、分析和放射学参数完全解决,正如本例患者所发生的那样。迄今为止报告的病例很少,这表明需要进行长期随访研究,以确定其与其他疾病的预后和关联频率。
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