Gastro-oesophageal reflux and "epileptic" attacks: casually associated or related? Efficiency of antireflux surgery: a case report.

Chirurgia italiana Pub Date : 2009-01-01
Eugenio Fiorentino, Gianni Pantuso, Alessia Cusimano, Stefania Latteri, Achille Mastrosimone, Calogero Cipolla
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Abstract

Although a possible link between gastro-oesophageal reflux disease (GORD) and obstructive sleeping apnoea has already been reported in the literature, there has never been any suggestion of an association with epilepsy, and epileptic attacks have not so far been included among gastro-oesophageal reflux disease symptoms. We report the case of a patient with gastro-oesophageal reflux disease associated with a sliding hiatus hernia, a short oesophagus and oesophagitis, who for the last ten years had not only presented the typical symptoms of gastrooesophageal reflux, but also symptoms of obstructive sleep apnoea and epileptic-like attacks occurring occasionally and only during sleep. Partial posterior fundoplication was performed and considerably reduced the reflux symptoms, and in addition brought about a drastic decrease in the number of epileptic-like attacks. Our case suggests that epileptic-like episodes in patients with obstructive sleeping apnoea may well be linked to the simultaneous presence of GORD associated with hiatus hernia, and surgical treatment of GORD may bring about an improvement of the neurological problems.

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胃食管反流与“癫痫”发作:偶然关联还是相关?抗反流手术疗效1例报告。
虽然已有文献报道胃食管反流病(GORD)与阻塞性睡眠呼吸暂停之间可能存在联系,但从未有任何迹象表明其与癫痫有关,并且癫痫发作迄今未被纳入胃食管反流病症状。我们报告一例胃食管反流病合并滑动裂孔疝、短食管和食管炎的患者,在过去的十年中,他不仅表现出典型的胃食管反流症状,而且还表现出阻塞性睡眠呼吸暂停和癫痫样发作的症状,偶尔发生且仅在睡眠中发生。部分后侧基底部复制术大大减轻了反流症状,并大大减少了癫痫样发作的次数。我们的病例表明,阻塞性睡眠呼吸暂停患者的癫痫样发作可能与同时存在的裂孔疝相关的GORD有关,GORD的手术治疗可能会改善神经系统问题。
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