[Study of the conpsumption of innapropiate medicaments in elder hospitalized in the Internal Medicine Service].

Anales De Medicina Interna Pub Date : 2008-06-01
F Blasco Patiño, R Pérez Maestu, J Martínez López de Letona, A I Jiménez, M J García Navarro
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Abstract

Background: The elderly patients are characterized by the high degree of polymedication. This factor is the most important in the appearance of adverse effects (EAD). The study of the medicaments helps to establish which are inappropriate and therefore they must move back, diminishing of this form EAD's possibility.

Patients and method: Prospective and observacional Study. Criterion of incorporation: patients of > 64 years old, hospitalized in an Internal Medicine Service. There were defined as inappropriate medicament the medicines of low therapeutic utility, them not indicated, and the inadequate ones for the elder. By means of the SPSS 11.5 program the possible variables related with the consumption were analyzed.

Results: 172 elders were included in the study. The average of medicines for person and day belonged to 5.34 (0-15). 52.5% was consuming an inappropriate medicament (36.6% inadequate for the elder, 15% not indicated, and 12% UTBs). The analysis multivariant associates the consumption of these medicaments with a major number of diseases (p < 0.012), to a major consumption of medicines (p < 0.001) and to the origin of the nursing residences (p < 0.001). Only the consumption of medicaments not adapted for the elder is associated with increase of EAD.

Conclusion: The half of the elders takes at least a medicament of unnecessary form, and the majority of these medicaments favors appearance of EAD.

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[内科住院老年人内丙酸类药物使用情况研究]。
背景:老年患者多药联用程度高。这个因素在不良反应(EAD)的出现中是最重要的。药物的研究有助于确定哪些是不合适的,因此他们必须撤回,减少这种形式的EAD的可能性。患者和方法:前瞻性和观察性研究。纳入标准:年龄> 64岁,在内科医院住院的患者。不适宜用药的定义为治疗效用低、无指征、老年人用药不足。采用SPSS 11.5统计软件对与消费相关的可能变量进行分析。结果:172名老年人纳入研究。每人日平均用药5.34次(0 ~ 15次)。52.5%的患者服用了不适当的药物(36.6%的患者不适合老年人,15%的患者没有用药指示,12%的患者使用utb)。多变量分析将这些药物的消费与主要疾病数量(p < 0.012)、药物的主要消费(p < 0.001)和养老院的来源(p < 0.001)联系起来。只有服用不适合老年人的药物才与EAD增加有关。结论:半数以上的老年人至少服用过一种形式不必要的药物,且这些药物大多有利于EAD的出现。
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