Chronic pelvic pain syndromes: clinical, urodynamic, and urothelial observations.

Charles W Butrick, Dan Sanford, Qingijiang Hou, Jonathan D Mahnken
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引用次数: 40

Abstract

Introduction/methods: A cohort of 408 patients with bladder pain syndrome/interstitial cystitis (BPS/IC) was evaluated, and findings were discussed in this retrospective chart review.

Results: Based on the chief complaints, they were divided into four subgroups: BPS/IC (n = 157), CPP (n = 98), vulvodynia/dyspareunia (n = 40), and "other" (n = 113). Similar findings were found in all four subgroups: complaints of voiding dysfunction (70%), dyspareunia (54%), mean PUF score of 15.9 +/- 6.4, and a positive potassium sensitivity test in 83%. Urodynamics revealed a maximal urethral pressure of 131 cm of water and an abnormal uroflow in 80%. Urothelial therapy in the form of intravesical therapeutic anesthetic cocktails provided benefit in all groups (50%, 67%, 73%, and 77% for vulvodynia, CPP, BPS/IC, "other").

Conclusions: All subgroups had similar findings and response to therapy. Five to 10% of patients with chief complaints of stress or urge incontinence or prolapse were also found to have BPS/IC.

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慢性盆腔疼痛综合征:临床、尿动力学和尿路上皮观察。
介绍/方法:对408例膀胱疼痛综合征/间质性膀胱炎(BPS/IC)患者进行队列评估,并在此回顾性图表回顾中讨论结果。结果:根据主诉分为4个亚组:BPS/IC (n = 157)、CPP (n = 98)、外阴痛/性交困难(n = 40)和“其他”(n = 113)。在所有四个亚组中都发现了类似的结果:排尿功能障碍(70%),性交困难(54%),PUF平均评分15.9 +/- 6.4,钾敏感试验阳性83%。尿动力学显示最大尿道压力为131厘米水,80%的患者尿流异常。膀胱内治疗性麻醉鸡尾酒形式的尿路上皮治疗在所有组中都有益处(50%,67%,73%和77%的外阴痛,CPP, BPS/IC,“其他”)。结论:所有亚组有相似的发现和对治疗的反应。5 - 10%的主诉为压力或急迫性尿失禁或脱垂的患者也被发现有BPS/IC。
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