[Efficiency of retrosternal lymphotropic chemotherapy in the treatment of new cases of destructive pulmonary tuberculosis].

B S Kibrik, A V Zakharov
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Abstract

The efficiency of treatment was evaluated in 2 groups of new tuberculosis cases discharging drug-resistant Mycobacterium tuberculosis. The authors' method of retrosternal lymphotropic administration of drugs was used in the complex of treatment in a study group of 96 patients; a control group (n = 93) received only combined chemotherapy. The treatment method showed a high efficiency in the treatment of new cases of destructive pulmonary tuberculosis, including acutely progressive forms and caseous pneumonia. Bacterial discharge cessation and decay cavity closure were increased by 26.9% and 27.2%, respectively. The abacillation rate increment was 32.9% for acutely progressive processes and 41.2% for caseous pneumonia. The authors show the efficiency of the method in treating bronchial or laryngeal tuberculosis and the expediency of applying the retrosternal procedure during preoperative preparation.

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[胸骨后淋巴细胞化疗治疗新发破坏性肺结核的疗效]。
对两组新发耐药结核分枝杆菌出院病例进行疗效评价。研究组96例患者采用胸骨后淋巴细胞给药的综合治疗方法;对照组(n = 93)仅接受联合化疗。该治疗方法在治疗新发破坏性肺结核(包括急性进展型和干酪性肺炎)方面显示出高效率。细菌排出停止率和龋齿闭合率分别提高26.9%和27.2%。急性进展性肺炎的消融率增加32.9%,干酪性肺炎的消融率增加41.2%。作者证明了该方法治疗支气管或喉部结核的有效性,以及在术前准备时应用胸骨后手术的便捷性。
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[Vaccine prophylaxis of tuberculosis: implication and problems]. [Prevalence of tuberculosis among children and adolescents in the Russian Federation: analysis of official statistics]. [Analysis of the rates of infection and incidence of tuberculosis in children from a poor epidemic-situation area in 2001 to 2006]. [Clinical and epidemiological features of tuberculosis ostitis in BCG-vaccinated children]. [Detection of tuberculosis in Moscow adolescents].
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