Letting go: modification of cell adhesion during apoptosis.

Journal of Biology Pub Date : 2009-01-01 Epub Date: 2009-05-28 DOI:10.1186/jbiol152
Magali Suzanne, Hermann Steller
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引用次数: 22

Abstract

Apoptosis appears to be a carefully orchestrated process for the ordered dismantling of cells. A recent paper in BMC Developmental Biology shows that the disassembly of adherens junctions during apoptosis in Drosophila is progressive and requires the amino-terminal cleavage of the beta-catenin Armadillo by the apoptotic effector caspase DrICE.

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放手:细胞凋亡过程中细胞粘附的改变。
细胞凋亡似乎是一个精心安排的有序拆除细胞的过程。最近发表在《BMC发育生物学》杂志上的一篇论文表明,果蝇凋亡过程中粘附连接的拆卸是渐进的,需要凋亡效应caspase DrICE对-catenin Armadillo的氨基端进行切割。
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