[Laparoscopic total gastrectomy for multifocal gastric GIST: a case report and review of the literature].

Chirurgia italiana Pub Date : 2009-03-01
Luca Maria Siani, Fabrizio Ferranti, Alberto Stefanuto, Marco Benedetti, Alberto Quintiliani
{"title":"[Laparoscopic total gastrectomy for multifocal gastric GIST: a case report and review of the literature].","authors":"Luca Maria Siani,&nbsp;Fabrizio Ferranti,&nbsp;Alberto Stefanuto,&nbsp;Marco Benedetti,&nbsp;Alberto Quintiliani","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Gastrointestinal stromal tumours (GISTs) are the most common mesenchymal tumours of the GI tract, deriving from interstitial Cajal cell degeneration. Over 95% of GISTs express CD-117 and CD-34, thus differing from other mesenchymal-derived tumours. The aim of this study was to evaluate our experience with a multifocal GIST, treated by laparoscopic total gastrectomy, and review the literature. A 74-year-old man with a preoperative diagnosis of sub-cardial GIST, obtained by endoscopy, CT scan and endoscopic ultrasound, was submitted to laparoscopic total gastrectomy with an end-to-side oesophago-jejunal anastomosis, using the Or-Vil system. GISTs account for only 1% of all GI tumours, with a variable behaviour, from indolent forms to aggressive tumours with potential for hepatic and peritoneal metastasis. Surgery is the cornerstone of therapy, the aim being to obtain an R0 resection, so as to minimise the risk of recurrence. Laparoscopic total gastrectomy is an excellent solution for their treatment, with possible adjuvant therapy based on imatinib-mesylate, for high-risk GIST.</p>","PeriodicalId":75700,"journal":{"name":"Chirurgia italiana","volume":"61 2","pages":"199-203"},"PeriodicalIF":0.0000,"publicationDate":"2009-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chirurgia italiana","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Gastrointestinal stromal tumours (GISTs) are the most common mesenchymal tumours of the GI tract, deriving from interstitial Cajal cell degeneration. Over 95% of GISTs express CD-117 and CD-34, thus differing from other mesenchymal-derived tumours. The aim of this study was to evaluate our experience with a multifocal GIST, treated by laparoscopic total gastrectomy, and review the literature. A 74-year-old man with a preoperative diagnosis of sub-cardial GIST, obtained by endoscopy, CT scan and endoscopic ultrasound, was submitted to laparoscopic total gastrectomy with an end-to-side oesophago-jejunal anastomosis, using the Or-Vil system. GISTs account for only 1% of all GI tumours, with a variable behaviour, from indolent forms to aggressive tumours with potential for hepatic and peritoneal metastasis. Surgery is the cornerstone of therapy, the aim being to obtain an R0 resection, so as to minimise the risk of recurrence. Laparoscopic total gastrectomy is an excellent solution for their treatment, with possible adjuvant therapy based on imatinib-mesylate, for high-risk GIST.

分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
[腹腔镜全胃切除术治疗多灶性胃间质瘤:1例报告及文献复习]。
胃肠道间质瘤(gist)是胃肠道最常见的间质肿瘤,起源于间质Cajal细胞变性。超过95%的gist表达CD-117和CD-34,因此不同于其他间质源性肿瘤。本研究的目的是评估腹腔镜全胃切除术治疗多灶性GIST的经验,并回顾相关文献。一名74岁男性,术前经内镜、CT扫描和内镜超声诊断为心下胃肠道间质瘤,采用Or-Vil系统行腹腔镜全胃切除术,吻合端侧食道空肠。胃肠道间质瘤仅占所有胃肠道肿瘤的1%,其表现各异,从惰性形式到侵袭性肿瘤,有可能发生肝脏和腹膜转移。手术是治疗的基石,目的是获得R0切除,以尽量减少复发的风险。对于高危GIST,腹腔镜全胃切除术是一种很好的治疗方案,可能的辅助治疗是甲磺酸伊马替尼。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
[Chylous ascites]. [Nipple discharge]. Gastric Lipoma Traumatic diaphragmatic injuries. [Treatment of biliary lesions due to cholecystectomy].
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1