[Oral medication via feed and water -- pharmacological aspects].

Manfred Kietzmann, Wolfgang Bäumer
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Abstract

By treatment of single animals or a live stock a treatment regimen has to be chosen, which guarantees a sufficient concentration of the administered drug in the target tissue. On the other hand, particular care has to be taken to avoid that single animals get a too high, intolerable dose of the administered drug. These elementary requirements must be met by the attending veterinarian.The treatment schedule must be in line with the current phamaceutical law. Some of the most outstanding problems associated with application via feed and water are discussed. Crucial factors apart from practicability are the bioavailability depending on pharmaceutical form and the avoidance of displacements of drugs. Future efforts should focus on the optimization of oral medication.

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[通过饲料和水口服药物-药理学方面]。
通过治疗单个动物或活畜,必须选择一种治疗方案,以保证给药药物在目标组织中的足够浓度。另一方面,必须特别小心,以避免单个动物获得过高的,难以忍受的剂量的药物。这些基本要求必须由主治兽医满足。治疗计划必须符合现行的药法。讨论了与饲料和水施用有关的一些最突出的问题。除了实用性之外,关键因素是取决于药物形式的生物利用度和避免药物置换。今后的工作重点应放在口服药物的优化上。
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