[Surgical treatment place in the management of prostate cancer: report of 96 cases].

Dakar medical Pub Date : 2008-01-01
B Diao, B Fall, P A Fall, C Ze Ondo, A Odzebe, Y Sow, A K Ndoye, M Ba, B A Diagne
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Abstract

Introduction: The goal of this study is to access the surgical management of the prostate cancer.

Patients and methods: It was a retrospective study including 96 cases of prostate cancer between June 2002 and December 2004. Parameters studied for every patient was: age, the complaints, results of rectal digital examination, the initial TPSA rate, gleason score, results of extension, the clinical grade according to TNM 2002 classification, the treatment and the future of treated patients.

Results: The mean age of our patients was 70.9 years with extremes of 50 years and 93 years. The complaints at presentation were dominated by prostatism (43.5%) and urine retention (37.7%). At rectal digital examination, the prostate was suspicious of cancer in 42.7%. The majority of our patients (79.8%) had a TPSA rate superior to 20 ng/ml. The examination revealed that the tumour was an adenocarcinoma in all patients. The majority of our patients (50.3%) had a gleason score inferior to 7. The extension outcome revealed: a loco-regional extension in 63 patients, dorso-lombar bone metastases in 19 patients and absence of secondary localisation in 14 patients. The repartition of patients according TNM classification was as following: T1 (1%), T2 (14.6%), T3 (18.8%) and T4 (65.6%). The patients were managed as following: bladder neck resection (surgically or endoscopically), pulpectomy and radical prostatectomy.

Conclusion: To ameliorate the prostate cancer management, the highlights of radical prostatectomy is imperative as the spreading of endoscopic surgery in the place of opening surgery.

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【手术治疗在前列腺癌治疗中的地位:附96例报告】。
前言:本研究的目的是探讨前列腺癌的外科治疗。患者和方法:回顾性研究包括2002年6月至2004年12月期间的96例前列腺癌患者。每位患者的研究参数为:年龄、主诉、直肠指诊结果、TPSA初始率、gleason评分、延伸结果、TNM 2002分级的临床分级、治疗情况及治疗患者的未来。结果:患者平均年龄为70.9岁,极端年龄为50岁和93岁。以前列腺增生(43.5%)和尿潴留(37.7%)为主。直肠指诊中有42.7%的人怀疑前列腺癌。我们的大多数患者(79.8%)的TPSA率高于20 ng/ml。检查显示所有患者的肿瘤均为腺癌。大多数患者(50.3%)gleason评分低于7分。扩展结果显示:63例患者局部-区域扩展,19例患者腰背骨转移,14例患者无继发定位。根据TNM分型对患者进行再划分:T1(1%)、T2(14.6%)、T3(18.8%)、T4(65.6%)。患者的治疗方法如下:膀胱颈切除术(手术或内镜下),髓质切除术和根治性前列腺切除术。结论:为了改善前列腺癌的治疗,根治性前列腺切除术的重点是内镜手术在开放手术中的扩展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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