[Radiation proctitis: description of two cases refractory to pharmacological treatment].

Chirurgia italiana Pub Date : 2009-05-01
Alessandro Piccolomini, Niccolò Francioli, Luigi Verre, Alfredo Guarnieri, Giuseppe Vuolo, Leonardo Di Cosmo, Andrea Tirone, Raffaele Chieca, Enrico Tucci, Anton Ferdinando Carli
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Abstract

Radiation proctitis, is a relatively frequent complication resulting from the direct or collateral irradiation of the rectum in radiotherapy treatment for genito-urinary or anorectal malignancies. The main symptoms are diarrhoea, tenesmus, proctorrhagia, anal pain, mucorrhoea and faecal incontinence. The evolution of chronic radiation proctitis requires treatment for related anaemia, anal incontinence and micturition disorders. The approach and type of treatment depend on the severity of the symptoms and on the endoscopic aspect, in relation to the response to previous medical therapy performed. In our experience, endoscopic treatment is the best choice in the presence of ongoing bleeding and the possible development of severe anaemia. The surgical option is mandatory in patients at high risk of sepsis, requiring a faecal diversion constructed using the Hartmann technique. We report two cases, observed during the last two years, one treated with endoscopic bipolar coagulation and the other with a double urinary and faecal diversion.

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【放射性直肠炎:2例药物治疗难治的描述】。
放射性直肠炎是在泌尿生殖系统或肛肠恶性肿瘤的放射治疗中,由于直肠直接或间接照射而引起的一种较为常见的并发症。主要症状为腹泻、下急、大出血、肛门疼痛、黏膜及大便失禁。慢性放射性直肠炎的发展需要治疗相关贫血,肛门失禁和排尿障碍。治疗的方法和类型取决于症状的严重程度和内窥镜方面,以及对先前进行的药物治疗的反应。根据我们的经验,在持续出血和可能发展为严重贫血的情况下,内镜治疗是最好的选择。对于脓毒症风险高的患者,手术是强制性的,需要使用Hartmann技术进行粪便转移。我们报告两个病例,在过去两年中观察到的,一个治疗与内镜双极性凝血和另一个双重尿和粪便转移。
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