Synthesis and thermal denaturation studies of covalently linked DNA triplexes.

Itaru Okamoto, Shota Ito, Takashi Ono, Akira Ono
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引用次数: 1

Abstract

We report on the synthesis and thermal stability of small covalently linked DNA triplexes. These modified triplexes were found to contain covalently linked T-T pairs at the edges, and thermal denaturation studies revealed that the covalent linking efficiently stabilized triplex formation.

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共价链DNA三联体的合成及热变性研究。
我们报道了小共价连接DNA三联体的合成和热稳定性。这些修饰的三聚体在边缘含有共价连接的T-T对,热变性研究表明,共价连接有效地稳定了三聚体的形成。
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