Utility of novel volumetric intravascular ultrasound analysis software for coronary artery disease.

Osaka city medical journal Pub Date : 2009-06-01

Takara Tsumori, Toru Kataoka, Yoshiki Kobayashi, Gao Xiaohui, Hiroaki Takeshita, Nobuyuki Shirai, Ryo Matsumoto, Shinji Nakata, Shoichi Ehara, Minoru Yoshiyama

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Abstract

Background: Volumetric intravascular ultrasound (IVUS) analysis has contributed significantly to the assessment of coronary artery disease. The aim of this study is to validate the novel IVUS analysis software (NICORAS) compared to the previously validated software (EchoPlaque).

Methods: Selected from clinical cases, we used 30 IVUS images that utilized motorized pullback at 0.5 mm/sec. Judging from at least two vascular landmarks, identical coronary artery segments were selected and analyzed with two software systems (NICORAS and EchoPlaque). Lumen and external elastic membrane (EEM) borderlines were traced at every 0.5 mm interval. Plaque area was calculated as EEM minus lumen area. Then, volumetric IVUS data were calculated using interpolated frame data from which lumen, EEM, and plaque volume were computed.

Results: The average analyzed coronary segment was 15.4 +/- 4.3 mm. There was excellent agreement between NICORAS and EchoPlaque for lumen volume (r = 0.999, p < 0.0001), EEM volume (r= 0.999, p < 0.0001), and plaque volume (r = 0.998, p < 0.0001).

Conclusion: The new volumetric IVUS analysis software provided IVUS data similar to previously examined software.

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新型冠状动脉疾病血管内超声分析软件的应用。

背景:容量血管内超声(IVUS)分析对冠状动脉疾病的评估有重要贡献。本研究的目的是验证新型IVUS分析软件(NICORAS)与先前验证的软件(EchoPlaque)的对比。方法:从临床病例中选择30张IVUS图像，采用0.5 mm/sec的电动回拉。根据至少两个血管标志，选择相同的冠状动脉段，并使用NICORAS和EchoPlaque两种软件系统进行分析。每隔0.5 mm追踪管腔和外弹性膜(EEM)边界。斑块面积计算为EEM减去管腔面积。然后，使用内插帧数据计算容积IVUS数据，从中计算管腔、EEM和斑块体积。结果:冠状动脉段平均为15.4±4.3 mm。NICORAS和EchoPlaque在管腔体积(r= 0.999, p < 0.0001)、EEM体积(r= 0.999, p < 0.0001)和斑块体积(r= 0.998, p < 0.0001)方面具有极好的一致性。结论:新的体积IVUS分析软件提供的IVUS数据与以前检测的软件相似。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Osaka city medical journal

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