Life and death as a T lymphocyte: from immune protection to HIV pathogenesis.

Nienke Vrisekoop, Judith N Mandl, Ronald N Germain
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引用次数: 11

Abstract

Detailed analysis of T cell dynamics in humans is challenging and mouse models can be important tools for characterizing T cell dynamic processes. In a paper just published in Journal of Biology, Marques et al. suggest that a mouse model with its activated CD4(+) T cells are deleted has relevance for HIV infection.

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作为T淋巴细胞的生与死:从免疫保护到HIV发病机制。
人体T细胞动力学的详细分析具有挑战性,小鼠模型可以成为表征T细胞动力学过程的重要工具。在刚刚发表在《生物学杂志》上的一篇论文中,Marques等人认为,一个被激活的CD4(+) T细胞被删除的小鼠模型与HIV感染有关。
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