Growth in Noonan syndrome.

Hormone research Pub Date : 2009-12-01 Epub Date: 2009-12-22 DOI:10.1159/000243776
B J Otten, C Noordam
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引用次数: 27

Abstract

Growth failure in Noonan syndrome is mainly postnatal of character and is dominated by slow maturation and late puberty. The postnatal early decline seems to be an intrinsic part of the syndrome. Reported adult heights are about -2 SD and are indicative of a secular trend.

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努南综合征的生长。
努南综合征的生长衰竭主要发生在出生后,以发育迟缓和青春期延迟为主。产后早期衰退似乎是该综合征的固有部分。报告的成人身高约为-2标准差,表明了长期趋势。
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来源期刊
Hormone research
Hormone research 医学-内分泌学与代谢
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Growth hormone therapy in Noonan syndrome: growth response and characteristics. GH therapy in Noonan syndrome: Review of final height data. Growth hormone and the heart in Noonan syndrome. Response to growth hormone in short children with Noonan syndrome: correlation to genotype. Genetic and pathogenetic aspects of Noonan syndrome and related disorders.
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