Microarray data analysis of gene expression evolution.

Honghuang Lin
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Abstract

Microarrays are becoming a widely used tool to study gene expression evolution. A recent paper by Wang and Rekaya describes a comprehensive study of gene expression evolution by microarray. The work provides a perspective to study gene expression evolution in terms of functional enrichment and promoter conservation. It was found that gene expression patterns are highly conserved in some biological processes, but the correlation between promoter and gene expression is insignificant. This scope of this work and future improvement to study gene expression evolution will be discussed in this article.

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基因表达进化的微阵列数据分析。
微阵列正在成为研究基因表达进化的一种广泛使用的工具。Wang和Rekaya最近发表的一篇论文描述了通过微阵列对基因表达进化的全面研究。这为从功能富集和启动子保护的角度研究基因表达进化提供了新的视角。研究发现,基因表达模式在某些生物学过程中具有高度保守性,但启动子与基因表达的相关性不显著。本文将讨论这项工作的范围和未来基因表达进化研究的改进。
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