Fishing for the signals that pattern the face.

Journal of Biology Pub Date : 2009-01-01 Epub Date: 2009-12-22 DOI:10.1186/jbiol205
Thomas F Schilling, Pierre Le Pabic
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引用次数: 16

Abstract

Zebrafish are a powerful system for studying the early embryonic events that form the skull and face, as a model for human craniofacial birth defects such as cleft palate. Signaling pathways that pattern the pharyngeal arches (which contain skeletal precursors of the palate, as well as jaws and gills) are discussed in light of a recent paper in BMC Developmental Biology on requirements for Hedgehog signaling in craniofacial development.

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寻找面部特征的信号。
斑马鱼是研究形成头骨和面部的早期胚胎事件的强大系统,作为人类颅面出生缺陷(如腭裂)的模型。根据BMC发育生物学最近的一篇关于颅面发育中Hedgehog信号通路需求的论文,讨论了信号通路对咽弓(包含腭、颌骨和鳃的骨骼前体)的影响。
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