Bunched and Madm: a novel growth-regulatory complex?

Journal of Biology Pub Date : 2010-01-01 Epub Date: 2010-02-11 DOI:10.1186/jbiol219
Kieran F Harvey
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引用次数: 3

Abstract

By combining Drosophila genetics and proteomics Gluderer et al. report in this issue of Journal of Biology the isolation of a novel growth-regulatory complex consisting of Bunched and Madm. Future study of this complex will address the precise mechanism of growth control, regulation of complex activity, the interface with other growth pathways and a potential role in human cancer.

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丛莽:一种新的生长调控复合体?
通过结合果蝇遗传学和蛋白质组学,Gluderer等人在本期《生物学杂志》上报道了一种由bunch和Madm组成的新型生长调节复合体的分离。未来对该复合物的研究将探讨其生长控制的确切机制、复合物活性的调控、与其他生长途径的界面以及在人类癌症中的潜在作用。
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