[Recurrent goitre: our experience].

Chirurgia italiana Pub Date : 2009-09-01
Pietro Giorgio Calò, Massimiliano Tuveri, Giuseppe Pisano, Alberto Tatti, Fabio Medas, Marcello Donati, Angelo Nicolosi
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Abstract

Recurrence after conservative thyroid surgery ranges from 7 to 40%. Risk factors for recurrence are female sex, multiple nodules in the resected lobe and lack of postoperative LT4 therapy. Indications for reoperation are suspected malignancy, recurrent thyrotoxicosis and recurrent uninodular or multinodulare goitre. From 2002 to 2008, 2149 total thyroidectomies were performed. Ninety-two patients had a completion thyroidectomy. The indication was recurrent multinodular goitre in 81, recurrent thyrotoxicosis in 3, and suspected malignancy in 8. Bilateral completion thyroidectomy was performed in 63 cases, lobectomy in 27 cases, removal of a mediastinal recurrence in 1 case and removal of a pyramidal remnant in 1 case. Histological examination revealed papillary cancer in 18 patients and follicular cancer in 1. Mean operative time was 140 minutes (range: 60-260). All patients were submitted to a minimum follow-up of 6 months. Temporary hypoparathyroidism occurred in 36 patients (39.1%) and definitive hypoparathyroidism in 7 patients (7.6%). Transient recurrent laryngeal nerve palsy occurred in 3 cases (3.2%) and permanent nerve palsy in 1 (1.1%). In 3 cases (3.2%) surgical revision of haemostasis was necessary for postoperative haemorrhage. Total thyroidectomy is the treatment of choice in multinodular goitre. In the cases in which reoperation is necessary, the intervention must be performed by an experienced surgeon.

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复发性甲状腺肿:我们的经验。
保守甲状腺手术后复发率为7 - 40%。复发的危险因素为女性、切除肺叶内多发结节和术后缺乏LT4治疗。再次手术指征为疑似恶性肿瘤、复发性甲状腺毒症及复发性单结节性或多结节性甲状腺肿。从2002年到2008年,进行了2149例甲状腺全切除术。92例患者完成了甲状腺切除术。81例甲状腺结节复发,3例甲状腺毒症复发,8例疑似恶性肿瘤。双侧完全甲状腺切除术63例,肺叶切除术27例,纵隔复发切除1例,锥体残余切除1例。组织学检查显示乳头状癌18例,滤泡癌1例。平均手术时间140分钟(范围:60-260分钟)。所有患者均接受至少6个月的随访。暂时性甲状旁腺功能减退36例(39.1%),终末期甲状旁腺功能减退7例(7.6%)。短暂性喉返神经麻痹3例(3.2%),永久性神经麻痹1例(1.1%)。3例(3.2%)术后出血需要手术止血。甲状腺全切除术是多结节性甲状腺肿的首选治疗方法。在需要再手术的情况下,必须由经验丰富的外科医生进行干预。
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