Digestive Disease Week 2010. Turning Science into Medicine--part 1.

Idrugs Pub Date : 2010-07-01
Lisa Hodgkinson
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Abstract

The Digestive Disease Week 2010 conference, held in New Orleans, included topics covering new therapeutic developments in the field of gastroenterology, hepatology, endoscopy and gastrointestinal surgery. This conference report highlights selected presentations on the novel thiopurine-based immunosuppressive agents B-0N and E-1 (both Giuliani SpA/Friedrich-Alexander-Universitaet Erlangen-Nuernberg); the investigation of ML-3403 (c-a-i-r biosciences GmbH), a p38 MAPK inhibitor for the treatment of chronic inflammatory disease; the development of ALV-003 (Alvine Pharmaceuticals Inc) for the treatment of celiac disease; efficacy studies of AST-120 in patients with irritable bowel syndrome; and a clinical trial evaluating linaclotide (Ironwood Pharmaceuticals Inc/Forest Laboratories Inc/Astellas Pharma Inc/Almirall Prodesfarma SA) withdrawal during chronic constipation therapy.

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2010年消化疾病周。将科学转化为医学——第一部分。
在新奥尔良举行的2010年消化疾病周会议的主题涵盖了胃肠病学、肝病学、内窥镜检查和胃肠外科领域的新治疗发展。本次会议报告重点介绍了新型基于硫嘌呤的免疫抑制剂B-0N和E-1 (Giuliani SpA/Friedrich-Alexander-Universitaet Erlangen-Nuernberg);ML-3403 (c-a-i-r biosciences GmbH)用于治疗慢性炎症性疾病的p38 MAPK抑制剂的研究;开发用于治疗乳糜泻的ALV-003 (Alvine Pharmaceuticals Inc .);AST-120治疗肠易激综合征的疗效研究;以及评估利那洛肽(Ironwood Pharmaceuticals Inc . /Forest Laboratories Inc . /Astellas Pharma Inc . /Almirall Prodesfarma SA)在慢性便秘治疗中停药的临床试验。
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Idrugs
Idrugs 医学-药学
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