Dabigatran: the anticoagulant we have long expected?

Georgios I Tagarakis, Dimos Karangelis, Marios E Daskalopoulos, Nikolaos B Tsilimingas
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引用次数: 1

Abstract

Many researchers have until now united their efforts in the endeavor to discover new anticoagulants, which would be simpler to use and safer to administer, so that patients would avoid both thromboembolic events as well as life threatening episodes of bleeding. One of these agents, that is hereby presented along with patents, is dabigatran, which promises much for the future, despite the fact that time and the awaited results of ongoing trials will be necessary for its establishment as a first-line anticoagulant. More specifically, based on the major trials of RELY and RECOVER, we could state that dabigatran has presented satisfactory outcomes in terms of bleeding and prevention of venous thromboembolism.

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达比加群:我们期待已久的抗凝剂?
到目前为止,许多研究人员已经联合起来努力发现新的抗凝剂,这种抗凝剂使用起来更简单,管理起来更安全,这样患者就可以避免血栓栓塞事件和危及生命的出血发作。其中一种药物是达比加群(dabigatran),在此与专利一起提交,它对未来有很大的希望,尽管时间和正在进行的试验的等待结果对于将其确定为一线抗凝血剂是必要的。更具体地说,基于RELY和RECOVER的主要试验,我们可以说达比加群在出血和预防静脉血栓栓塞方面表现出令人满意的结果。
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