[Effect of systematic vaccination on the epidemiology of urlian parotiditis in the population of Bucharest].

Abstract

Objective: describe the mumps evolution during the time period that immediately followed the introduction of routine mumps vaccine into the Bucharest municipality's population.

Methods: observational, descriptive, and retrospective study. The temporal frequencies were taken from official reports of clinically confirmed mumps cases with annually sequence during the 1951-2001 period and monthly sequence during the 2002-2009 period of time respectively. The temporal frequencies were graphically represented in semilogarithmic scale; the temporal trend of the frequencies was estimated through linear regression.

Results: in the time period of 5 years subsequently to the introduction of mumps routine vaccination with two doses of measles-mumps-rubella triple vaccine, the following events intervened in the evolution of mumps in the population of Bucharest municipality: (a) starting with the year of 2006 the annual frequency of cases became constantly placed under the lower limit of 1000 cases of the prevaccine era's distribution, (b) starting with September 2005 the monthly frequency of mumps cases decreased under the lower limit of 100 cases of the prevaccine era's distribution, (c) the decline rhythm of the annual frequency account for 1156 units (r2 = 0.76; p = 0.03) and, (d) due to the herd protection effect induced by vaccine, decreasing affected all age groups.

Conclusions: although late implemented (in European context) the routine vaccination determined a fairly consistent declining of the mumps morbidity and very probably of the serious complications and/or sequels associated to natural disease, being in this way an outstanding achievement of preventive medicine