Comparison of vitreous and plasma levels of vascular endothelial growth factor, interleukin-6 and hepatocyte growth factor in diabetic and non-diabetic retinal detachment cases.

Annals of ophthalmology Pub Date : 2010-01-01
Nilufer Kocak, Inci Alacacioglu, Suleyman Kaynak, Mehmet Ali Ozcan, Olcayto Celik, Faize Yuksel, Ozden Piskin, Hakan Oner, Ali Osman Saatci, Mehmet Ergin
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Abstract

We compared the vitreous and plasma levels of proinflammatory cytokines in diabetic patients who underwent pars plana vitrectomy. Levels of proinflammatory cytokines in the vitreous were higher in the diabetic patients than the non-diabetics while the levels of plasma cytokines were similar. It is thought that this increase in the vitreous is effective in the progression of angiogenesis and the development of proliferative diabetic retinopathy.

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糖尿病与非糖尿病性视网膜脱离患者玻璃体及血浆血管内皮生长因子、白细胞介素-6及肝细胞生长因子水平的比较
我们比较了玻璃体切除术后糖尿病患者玻璃体和血浆中促炎细胞因子的水平。糖尿病患者玻璃体中促炎细胞因子水平高于非糖尿病患者,血浆细胞因子水平相似。据认为,这种玻璃体的增加对血管生成的进展和增殖性糖尿病视网膜病变的发展是有效的。
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Annals of ophthalmology
Annals of ophthalmology 医学-眼科学
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