Lorance Wilson, Sarah Cross, James Gimzewski, JianYu Rao
{"title":"Nanocytology: a novel class of biomarkers for cancer management.","authors":"Lorance Wilson, Sarah Cross, James Gimzewski, JianYu Rao","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Recently, cellular mechanical properties have received increasing attention as a potential biophysical marker for cancer cells. The analysis of mechanical profiles at the single-cell level may provide information that is potentially useful to assess tumor prognosis and response to therapy. This feature review discusses a novel nanocytology approach that combines traditional morphology assessment, molecular analysis and nanomechanical analysis of cancer cells.</p>","PeriodicalId":55031,"journal":{"name":"Idrugs","volume":"13 12","pages":"847-51"},"PeriodicalIF":0.0000,"publicationDate":"2010-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Idrugs","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
Recently, cellular mechanical properties have received increasing attention as a potential biophysical marker for cancer cells. The analysis of mechanical profiles at the single-cell level may provide information that is potentially useful to assess tumor prognosis and response to therapy. This feature review discusses a novel nanocytology approach that combines traditional morphology assessment, molecular analysis and nanomechanical analysis of cancer cells.
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