Patented applications of gene silencing in plants: manipulation of traits and phytopathogen resistance.

Ruben Alvarez-Fernandez
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引用次数: 1

Abstract

RNA silencing is the name of a broad family of phenomena including RNA interference (RNAi) in animals and basal eukaryotes, quelling in fungi and posttranscriptional gene silencing (PTGS) in plants. PTGS is a fertile research field and since its discovery many applications have been developed related to plant breeding. This minireview summarizes those patents which apply engineered gene silencing to specific problems. The range of inventions is divided in two main sections: manipulation of traits and resistance to phytopathogens and pests. Subtopics like manipulation of tolerances to abiotic stress, alteration of lignin, biofactories, alkaloids biosynthesis and flowering time fall within the first section, and introduction of resistances to insects, nematodes, bacteria, virus and fungi can be found within the second one.

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基因沉默在植物中的专利应用:性状操纵和植物病原菌抗性。
RNA沉默是一系列广泛现象的统称,包括动物和基础真核生物中的RNA干扰(RNAi)、真菌中的抑制(quelling)和植物中的转录后基因沉默(PTGS)。PTGS是一个丰富的研究领域,自从它被发现以来,已经开发了许多与植物育种有关的应用。本文综述了应用工程基因沉默技术解决具体问题的专利。发明范围分为两个主要部分:性状操纵和对植物病原体和害虫的抗性。诸如操纵对非生物胁迫的耐受性、木质素的改变、生物工厂、生物碱的生物合成和开花时间等子主题属于第一部分,而对昆虫、线虫、细菌、病毒和真菌的抗性的引入可以在第二部分找到。
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