Frequency of metabolic syndrome in patients with type-2 diabetes.

Q3 Medicine Journal of Ayub Medical College, Abbottabad : JAMC Pub Date : 2010-01-01
Nasir Ahmed, Tauqir Ahmad, Syed Javed Hussain, Muhammad Javed
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Abstract

Background: Diabetes, Hypertension, Obesity and Ischaemic Heart Disease have become a problem of public health magnitude with substantial economic burden both in the developed as well as the developing countries. Obesity is quite frequent in Type 2 diabetics and also plays a central role in causing Metabolic Syndrome (MetS). Metabolic Syndrome significantly increases the incidence of cardiovascular complications. This study was done to determine the frequency of MetS in our Type 2 diabetic patients as most of the components of MetS can be modified and identifying/managing these at an early stage might be of considerable help in reducing cardiovascular complications.

Methods: This cross-sectional study was done in Medical 'B' and Medical 'A' wards of Ayub Teaching Hospital, Abbottabad from Nov, 08 to April, 09. Type 2 Diabetic patients aged above 40 years who gave informed consent were included in the study. Data was collected through a structured proforma. Frequency of Metabolic Syndrome was estimated according to the IDF consensus worldwide definition of the MetS.

Results: Of the 100 patients enrolled in this study 56 were females and 44 were males with a mean age of 59.9 years. Out of these 100 participants seventy six (76%) were diagnosed to have metabolic syndrome. Of the 56 females, forty eight (85.71%) were having metabolic syndrome while twenty eight (63.63%) of the 44 male participants were having the syndrome. The difference was statistically significant (p < 0.05).

Conclusion: Frequency of MetS was found to be significantly high in this study with female preponderance. All the components, except Hypertension were more frequent in females. Diabetic patients with metabolic syndrome need more aggressive approach in management so as to decrease the incidence of cardiovascular complications.

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2型糖尿病患者代谢综合征的发生率。
背景:无论是在发达国家还是在发展中国家,糖尿病、高血压、肥胖和缺血性心脏病都已成为具有重大经济负担的公共卫生问题。肥胖在2型糖尿病患者中相当常见,并且在引起代谢综合征(MetS)中起着核心作用。代谢综合征显著增加心血管并发症的发生率。这项研究的目的是确定2型糖尿病患者的代谢代谢的频率,因为代谢代谢的大部分成分是可以改变的,在早期阶段识别/管理这些成分可能对减少心血管并发症有很大的帮助。方法:本横断面研究于2008年11月至2009年4月在阿伯塔巴德Ayub教学医院医学“B”和医学“A”病房进行。年龄在40岁以上且知情同意的2型糖尿病患者纳入研究。数据通过结构化形式表收集。代谢综合征的发生频率根据世界范围内的代谢综合征定义进行估计。结果:纳入研究的100例患者中,女性56例,男性44例,平均年龄59.9岁。在这100名参与者中,76人(76%)被诊断患有代谢综合征。56名女性中有48人(85.71%)患有代谢综合征,44名男性中有28人(63.63%)患有代谢综合征。差异有统计学意义(p < 0.05)。结论:本研究发现met的发生频率明显高,且以女性为主。除高血压外,其余成分在女性中较常见。糖尿病代谢综合征患者需要更积极的治疗方法,以减少心血管并发症的发生率。
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