Radiolabeling of cramoll 1,4: evaluation of the biodistribution.

International Journal of Peptides Pub Date : 2011-01-01 Epub Date: 2011-06-30 DOI:10.1155/2011/945397
Beatriz Ferreira de Carvalho Patricio, Maria Helena Madruga Lima-Ribeiro, Maria Tereza Dos Santos Correia, Ana Maria Dos Anjos Carneiro-Leão, Marta de Souza Albernaz, Thiago Barboza, Sergio Augusto Lopes de Souza, Ralph Santos-Oliveira
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引用次数: 7

Abstract

The cramoll 1,4 is a well-studied lectin. However, few studies about its biodistribution have been done before. In this study, we radiolabeled the cramol 1,4 with Tc-99m and analyzed the biodistribution. The results showed that the cramol has an abnormal uptake by the bowel with reflections on its clearance mechanism.

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cramoll 1,4的放射性标记:生物分布的评价。
克鲁尔1,4是一种经过充分研究的凝集素。然而,对其生物分布的研究很少。本研究用Tc-99m对克罗默尔1,4进行放射性标记,并分析其生物分布。结果表明,克罗莫尔在肠内摄取异常,反映了其清除机制。
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