Beatriz Ferreira de Carvalho Patricio, Maria Helena Madruga Lima-Ribeiro, Maria Tereza Dos Santos Correia, Ana Maria Dos Anjos Carneiro-Leão, Marta de Souza Albernaz, Thiago Barboza, Sergio Augusto Lopes de Souza, Ralph Santos-Oliveira
{"title":"Radiolabeling of cramoll 1,4: evaluation of the biodistribution.","authors":"Beatriz Ferreira de Carvalho Patricio, Maria Helena Madruga Lima-Ribeiro, Maria Tereza Dos Santos Correia, Ana Maria Dos Anjos Carneiro-Leão, Marta de Souza Albernaz, Thiago Barboza, Sergio Augusto Lopes de Souza, Ralph Santos-Oliveira","doi":"10.1155/2011/945397","DOIUrl":null,"url":null,"abstract":"<p><p>The cramoll 1,4 is a well-studied lectin. However, few studies about its biodistribution have been done before. In this study, we radiolabeled the cramol 1,4 with Tc-99m and analyzed the biodistribution. The results showed that the cramol has an abnormal uptake by the bowel with reflections on its clearance mechanism.</p>","PeriodicalId":14239,"journal":{"name":"International Journal of Peptides","volume":"2011 ","pages":"945397"},"PeriodicalIF":0.0000,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2011/945397","citationCount":"7","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Peptides","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/2011/945397","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2011/6/30 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 7
Abstract
The cramoll 1,4 is a well-studied lectin. However, few studies about its biodistribution have been done before. In this study, we radiolabeled the cramol 1,4 with Tc-99m and analyzed the biodistribution. The results showed that the cramol has an abnormal uptake by the bowel with reflections on its clearance mechanism.