Impact of a prenatal cognitive-behavioral stress management intervention on salivary cortisol levels in low-income mothers and their infants

IF 3.6 2区 医学 Q2 ENDOCRINOLOGY & METABOLISM Psychoneuroendocrinology Pub Date : 2011-11-01 DOI:10.1016/j.psyneuen.2011.04.002
Guido G. Urizar Jr. Ph.D. , Ricardo F. Muñoz Ph.D.
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引用次数: 95

Abstract

Recent findings suggest that elevated stress levels during the pre- and postpartum period are related to poor maternal and infant health outcomes; yet, few studies have prospectively examined the efficacy of stress management interventions on regulating stress levels among mothers and their infants. The current study examined whether a prenatal cognitive behavioral stress management (CBSM) intervention would be effective in regulating salivary cortisol (a biological marker of stress) and self-reported stress levels among mothers and their infants at six and 18 months postpartum, relative to two control groups. Our sample was comprised of predominantly Spanish-speaking, low-income women (80%; mean age = 25 ± 5 years) who were screened for depression during their second trimester of pregnancy (M = 16 ± 5 weeks of gestation). Women at high risk for depression [i.e., having either a past history of major depression or current elevated symptoms of depression (≥16 on CES-D)] were randomized to either a CBSM group (n = 24) or a usual care (UC) group (n = 33), while a low risk comparison (LRC) group (n = 29) was comprised of women not meeting either depression criteria. ANCOVA analyses demonstrated that: (1) infants of women in the CBSM and LRC groups had significantly lower cortisol levels than infants of women in the UC group at six months postpartum (p < .001); and (2) women in the CBSM group had lower cortisol levels than women in the UC group at 18 months postpartum (p < .01). These results suggest that prenatal CBSM interventions may be efficacious in regulating biological markers of stress among mothers and their infants, thereby decreasing their risk for developing health complications over time.

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产前认知行为压力管理干预对低收入母亲及其婴儿唾液皮质醇水平的影响
最近的研究结果表明,产前和产后压力水平升高与孕产妇和婴儿健康状况不佳有关;然而,很少有研究前瞻性地考察压力管理干预对调节母亲及其婴儿压力水平的效果。目前的研究调查了产前认知行为压力管理(CBSM)干预是否能有效调节产后6个月和18个月母亲及其婴儿的唾液皮质醇(压力的生物标志物)和自我报告的压力水平,相对于两个对照组。我们的样本主要由讲西班牙语的低收入女性组成(80%;平均年龄= 25±5岁),在妊娠中期(M = 16±5周)进行抑郁筛查。抑郁症高风险妇女[即有严重抑郁症病史或当前抑郁症状升高(≥16)]被随机分为CBSM组(n = 24)或常规护理组(n = 33),而低风险比较组(n = 29)由不符合抑郁标准的妇女组成。ANCOVA分析表明:(1)产后6个月,CBSM组和LRC组妇女的婴儿皮质醇水平显著低于UC组妇女的婴儿(p <措施);(2)产后18个月,CBSM组的皮质醇水平低于UC组(p <. 01)。这些结果表明,产前CBSM干预可能有效调节母亲及其婴儿的压力生物学标志物,从而降低他们随着时间的推移发生健康并发症的风险。
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来源期刊
Psychoneuroendocrinology
Psychoneuroendocrinology 医学-精神病学
CiteScore
7.40
自引率
8.10%
发文量
268
审稿时长
66 days
期刊介绍: Psychoneuroendocrinology publishes papers dealing with the interrelated disciplines of psychology, neurobiology, endocrinology, immunology, neurology, and psychiatry, with an emphasis on multidisciplinary studies aiming at integrating these disciplines in terms of either basic research or clinical implications. One of the main goals is to understand how a variety of psychobiological factors interact in the expression of the stress response as it relates to the development and/or maintenance of neuropsychiatric illnesses.
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