Is conservative treatment with antibiotics the correct strategy for management of right colonic diverticulitis?: a prospective study.

Tae Jung Kim, In Kyu Lee, Jong Kyung Park, Yoon Suk Lee, Youn Si, Hun Jung, Hyung Jin Kim, Sang Chul Lee, Dae Young Cheung, Lee D Gorden, Seung Taek Oh
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引用次数: 14

Abstract

Purpose: The goals of this study were to identify whether conservative treatment with antibiotics in right colonic diverticulitis (RCD) patients, our empirical method used until now, is adequate and to determine how the natural history of RCD is affected by conservative treatment.

Methods: This study was designed as a case-control study. Group I was comprised of 12 patients who were managed conservatively, and clinical data were retrospectively collected. In group II, a total of 49 patients, diagnosed by using diagnostic criteria for RCD and managed conservatively, were prospectively included.

Results: The period of fasting was 2.7 days, and the hospital stay was 4.6 days in all patients. The intravenous and the oral antibiotic periods were 3.8 days and 9.8 days, respectively. There were no statistically significant differences in treatment results between the two groups except the duration of fasting and the hospitalization, and there were no complications under conservative treatment. Eight patients (13.1%) had recurrent diverticulitis during the follow-up period. The recurrence risk showed no significant difference between the groups. The RCD-free period after management was 60.1 months, and patients with recurrent RCD were treated by conservative treatment or laparoscopic surgery.

Conclusion: Conservative treatment with antibiotics is the optimal treatment of choice for RCD and shows no increase in complications.

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抗生素保守治疗是治疗右结肠憩室炎的正确策略吗?前瞻性研究。
目的:本研究的目的是确定抗生素保守治疗右结肠憩室炎(RCD)患者(我们目前使用的经验方法)是否足够,并确定保守治疗如何影响RCD的自然史。方法:本研究采用病例-对照研究。第一组12例患者采用保守治疗,回顾性收集临床资料。II组共纳入49例患者,采用RCD诊断标准诊断并进行保守治疗。结果:所有患者禁食时间为2.7 d,住院时间为4.6 d。静脉和口服抗生素疗程分别为3.8 d和9.8 d。两组治疗结果除禁食时间和住院时间差异无统计学意义,保守治疗无并发症发生。随访期间复发憩室炎8例(13.1%)。两组复发风险无显著性差异。治疗后无RCD期为60.1个月,复发RCD患者采用保守治疗或腹腔镜手术治疗。结论:抗生素保守治疗是RCD的最佳治疗选择,且无并发症增加。
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