Viktor Berge, Rolf Eigil Berg, Jon Roar Hoff, Nicolai Wessel, Aud Svindland, Steinar Johan Karlsen, Lars Magne Eri
{"title":"Five-year progression-free survival in 577 patients operated on with laparoscopic radical prostatectomy for localized prostate cancer.","authors":"Viktor Berge, Rolf Eigil Berg, Jon Roar Hoff, Nicolai Wessel, Aud Svindland, Steinar Johan Karlsen, Lars Magne Eri","doi":"10.3109/00365599.2011.604790","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>Laparoscopic radical prostatectomy (LRP) was introduced in the Department of Urology, Oslo University Hospital, in 2002. The aim of this study was to report mid-term oncology results and survival data.</p><p><strong>Material and methods: </strong>From February 2002 to November 2007, 582 consecutive patients with localized prostate cancer underwent LRP. Data were collected prospectively into a database.</p><p><strong>Results: </strong>Mean and median follow-up after LRP was 30.3 months (± 15.5) and 36.0 months (range 3-72). Five patients (1%) were lost during follow-up. Two patients died of prostate cancer during the study period and 10 patients died of other causes. The overall positive surgical margin (PSM) rate was 29% and decreased to 13% for the last 100 patients. The overall PSA progression-free survival (PFS) was 85% at 3 years and 73% at 5 years. Gleason score in the tumour specimen, pT stage and surgical margins were statistical significant independent predictors of biochemical PFS.</p><p><strong>Conclusion: </strong>These oncology results and 5-year PFS data after LRP are in line with other reports.</p>","PeriodicalId":21543,"journal":{"name":"Scandinavian Journal of Urology and Nephrology","volume":"46 1","pages":"8-13"},"PeriodicalIF":0.0000,"publicationDate":"2012-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/00365599.2011.604790","citationCount":"8","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Scandinavian Journal of Urology and Nephrology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3109/00365599.2011.604790","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2011/8/15 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 8
Abstract
Objective: Laparoscopic radical prostatectomy (LRP) was introduced in the Department of Urology, Oslo University Hospital, in 2002. The aim of this study was to report mid-term oncology results and survival data.
Material and methods: From February 2002 to November 2007, 582 consecutive patients with localized prostate cancer underwent LRP. Data were collected prospectively into a database.
Results: Mean and median follow-up after LRP was 30.3 months (± 15.5) and 36.0 months (range 3-72). Five patients (1%) were lost during follow-up. Two patients died of prostate cancer during the study period and 10 patients died of other causes. The overall positive surgical margin (PSM) rate was 29% and decreased to 13% for the last 100 patients. The overall PSA progression-free survival (PFS) was 85% at 3 years and 73% at 5 years. Gleason score in the tumour specimen, pT stage and surgical margins were statistical significant independent predictors of biochemical PFS.
Conclusion: These oncology results and 5-year PFS data after LRP are in line with other reports.
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