Drug utilization in intensive care units in a pediatric hospital.

Mario I Ortiz, Fabiola Ortega-Franco, Martha Bautista-Rivas, Georgina Romo-Hernández, Juan M López-Cadena, José A Copca-García
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Abstract

The main objective of the present study was to investigate the use of drugs in the pediatric intensive care units (PICUs) at a pediatric hospital. Data were equally collected from charts of PICUs of the Hospital del Niño DIF, Pachuca, Hidalgo, Mexico in 2007. The data included demographic, clinical data and those on drugs usage. A total of 45 patients were included at the study, all (100%) of whom received one or more drugs. Data were collected and 57 different drugs were given to the pediatric patients. The median number of drugs/inpatient was 6.9 (1-17). The therapeutic class most prescribed was anti- infective (30.6 % of all the prescriptions), followed by electrolytes (13.3 % of all the prescriptions) and gastrointestinal agents (12.9 % of all the prescriptions). KCI was the drug most commonly used (64.4 % of all the patients) followed by ranitidine and amikacin (both with 51.1 % of all the patients). As in many studies, the therapeutic class most used was the anti-infectives. Substantial variation exists in hospitalists' reported management of common pediatric conditions. To decrease undesirable variation in care, a stronger evidence base for inpatient pediatric care must be built.

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某儿科医院重症监护病房的药物使用情况
本研究的主要目的是调查儿科医院儿童重症监护病房(picu)的药物使用情况。数据同样从2007年墨西哥伊达尔戈Pachuca的Niño DIF医院picu的图表中收集。这些数据包括人口统计数据、临床数据和药物使用数据。该研究共纳入45例患者,所有患者(100%)均接受一种或多种药物治疗。收集数据并给儿童患者使用57种不同的药物。药物/住院患者中位数为6.9(1-17)。处方最多的治疗类是抗感染类(占处方总数的30.6%),其次是电解质类(占处方总数的13.3%)和胃肠类药物(占处方总数的12.9%)。KCI是最常用的药物(占所有患者的64.4%),其次是雷尼替丁和阿米卡星(均占所有患者的51.1%)。在许多研究中,最常用的治疗类是抗感染药物。医院医生对常见儿科疾病的处理报告存在实质性差异。为了减少护理中的不良变化,必须建立一个更强有力的儿科住院护理证据基础。
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