Polypoidal choroidal vasculopathy, diagnosis and management.

G Coppens, L Spielberg, A Leys
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Abstract

Polypoidal Choroidal Vasculopathy (PCV) was first identified in 1985. Initially considered to be rare, PCV is currently frequently diagnosed in patients of African and Asian descent. In Caucasians, PCV counts for 10% of cases of AMD, and for up to 85% of patients with hemorrhagic or exudative retinal pigment epithelial detachment. Although the clinical presentation can be suggestive, extensive investigation with the indispensable indocyanine green angiography, is required for confirmation of PCV. Treatment has to be considered in active disease threatening the macula. Photodynamic therapy with Verteporfin is required for closure of PCV complexes. Anti-VEGF treatment reduces associated macular edema.

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息肉样脉络膜血管病变的诊断和治疗。
息肉样脉络膜血管病变(Polypoidal Choroidal vascular pathy, PCV)于1985年首次被发现。PCV最初被认为是罕见的,目前在非洲和亚洲血统的患者中经常被诊断出来。在白种人中,PCV占AMD病例的10%,占出血性或渗出性视网膜色素上皮脱离患者的85%。虽然临床表现可能具有提示性,但需要广泛的调查和不可或缺的吲哚菁绿血管造影,以确认PCV。对于威胁黄斑的活动性疾病,必须考虑治疗。需要使用维替波芬进行光动力治疗来关闭PCV复合体。抗vegf治疗可减少相关的黄斑水肿。
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