[Bilateral simultaneous central retinal artery occlusion revealing giant cell arteritis].

K D Ayena, S L A Lawson, A Koffi, K Amegbor, M Pio, M I O Machihude, K Tchabia Nabroulaba, T Gaoussou, J Feys, P H Feys, F Forestier, K P Balo
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Abstract

Aim: To point out the importance of the early diagnosis of giant cell arteritis (GCA) (Horton's disease).

Materials and methods: a case report of a sudden bilateral blindness that had revealed GCA.

Case report: A 68-year old female patient with a history of elevated blood pressure and diabetes mellitus type 2, was examined in emergency for a right painful headache developed one week previously. In ophthalmological examination, her BCVA was 0.9 and P2 in both eyes. Diagnosis of Horton's disease was not initially done in spite of elevated erythrocytes sedimentation rate (ESR) at 30 mm, protein C reactive (CRP) at 19 mg/l. The patient consulted seven weeks later in emergency for a sudden bilateral blindness associated with severe headache, recent asthenia, and limping of the lower jaw. At that time, visual acuity was reduced to light perception in both eyes whereas ophthalmoscopy revealed a bilateral central retinal artery occlusion (CRAO). ESR was 74 mm and CRP 233 mg/I. Temporal artery biopsy confirmed the diagnosis of GCA. The patient was treated with systemic steroids without visual recovery.

Conclusion: This case outlines the importance of the early diagnosis of GCA in order to make possible to start treatment before the occurrence of irreversible complications.

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[双侧同时视网膜中央动脉闭塞显示巨细胞动脉炎]。
目的:指出巨细胞动脉炎(霍顿病)早期诊断的重要性。材料与方法:报告1例突发性双侧失明伴GCA的病例。病例报告:一名68岁女性患者,有高血压和2型糖尿病病史,1周前出现右侧头痛,急诊就诊。眼科检查BCVA为0.9,双眼为P2。尽管红细胞沉降率(ESR)升高至30mm,蛋白C反应(CRP)升高至19mg /l,但最初并未进行霍顿病的诊断。患者7周后因突然双侧失明伴严重头痛、近期乏力和下颌跛行就诊。当时,双眼视力下降到光感,而眼科检查显示双侧视网膜中央动脉闭塞(CRAO)。ESR为74 mm, CRP为233 mg/I。颞动脉活检证实GCA的诊断。患者接受全身性类固醇治疗,但视力未恢复。结论:本病例强调了早期诊断GCA的重要性,以便在不可逆并发症发生前开始治疗。
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