Heating pad for the bleeding: external warming during hemorrhage improves survival.

Ying Wang, Jianhua Feng, Guoxing You, Xuemei Kan, Longxiang Qiu, Gan Chen, Dawei Gao, Wei Guo, Lian Zhao, Hong Zhou
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引用次数: 9

Abstract

Background: Hypothermia is common during hemorrhagic shock. To warm the victims or not has been controversial. This study aims to investigate the effect of warming during the initial time of hemorrhage on body temperature, blood pressure, and survival in rat hemorrhagic shock models.

Methods: Forty anesthetized rats were divided into control group (n = 20) and warming group (n = 20). The rats of control group were placed on a wooden pad without heating, and the rats of warming group were placed on a heating pad maintained at 37°C ± 0.1°C. Blood withdrawal reached 40% of the total blood volume within 60 minutes. Numbers of survival rats, rectal temperature, and mean arterial pressure (MAP) were recorded when blood loss reached 0 (T0), 20% (T20), 30% (T30), and 40% (T40) of the total blood volume, respectively.

Results: Rectal temperature and MAP decrease gradually in both groups during hemorrhage. Warming continuously makes the rectal temperature of the warming group (36.68°C ± 0.63°C) slightly higher than that of the control group (36.17°C ± 0.69°C) at T0. The rectal temperature and MAP of the warming group are higher than that of the control group at T20, T30, and T40 (p < 0.05). Survival rates of the warming group are higher than that of the control group (p < 0.01).

Conclusions: Warming during hemorrhage may prevent exacerbation of hypothermia and hypotension and therefore improve survival.

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出血加热垫:出血时外部加热可提高存活率。
背景:低温在失血性休克中很常见。是否给受害者取暖一直存在争议。本研究旨在探讨出血初期加温对失血性休克模型大鼠体温、血压及存活的影响。方法:40只麻醉大鼠分为对照组(n = 20)和温敷组(n = 20)。对照组大鼠置于不加热的木垫上,加热组大鼠置于温度为37℃±0.1℃的加热垫上。60分钟内取血量达到总血容量的40%。当失血量分别达到总血容量的0 (T0)、20% (T20)、30% (T30)、40% (T40)时,记录存活大鼠数量、直肠温度和平均动脉压(MAP)。结果:两组患者出血时直肠温度和MAP逐渐下降。持续升温使升温组在T0时的直肠温度(36.68℃±0.63℃)略高于对照组(36.17℃±0.69℃)。加热组在T20、T30、T40时直肠温度、MAP均高于对照组(p < 0.05)。加热组的成活率高于对照组(p < 0.01)。结论:出血时加热可防止低温和低血压加重,从而提高生存率。
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来源期刊
Journal of Trauma-Injury Infection and Critical Care
Journal of Trauma-Injury Infection and Critical Care CRITICAL CARE MEDICINE-EMERGENCY MEDICINE
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3 months
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