Managing chronic pain with spinal cord stimulation.

Lawrence J Epstein, Marco Palmieri
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引用次数: 63

Abstract

Since its introduction as a procedure of last resort in a terminally ill patient with intractable cancer-related pain, spinal cord stimulation has been used to effectively treat chronic pain of varied origins. Spinal cord stimulation is commonly used for control of pain secondary to failed back surgery syndrome and complex regional pain syndrome, as well as pain from angina pectoris, peripheral vascular disease, and other causes. By stimulating one or more electrodes implanted in the posterior epidural space, the patient feels paresthesias in their areas of pain, which reduces the level of pain. Pain is reduced without the side effects associated with analgesic medications. Patients have improved quality of life and improved function, with many returning to work. Spinal cord stimulation has been shown to be cost effective as compared with conservative management alone. There is strong evidence for efficacy and cost effectiveness of spinal cord stimulation in the treatment of pain associated with intractable angina, failed back surgery syndrome, and complex regional pain syndrome. In this article, we review the history and pathophysiology of spinal cord stimulation, and the evidence (or lack thereof) for efficacy in common clinical practice.

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脊髓刺激治疗慢性疼痛。
自从脊髓刺激作为治疗难治性癌症相关疼痛的绝症患者的最后手段以来,脊髓刺激已被用于有效治疗各种原因的慢性疼痛。脊髓刺激常用于控制背部手术失败综合征和复杂区域疼痛综合征继发疼痛,以及心绞痛、周围血管疾病和其他原因引起的疼痛。通过刺激植入硬膜外后腔的一个或多个电极,患者在疼痛区域感到感觉异常,从而减轻疼痛程度。疼痛减轻,没有镇痛药物的副作用。患者的生活质量得到改善,功能得到改善,许多人重返工作岗位。与单纯保守治疗相比,脊髓刺激已被证明具有成本效益。有强有力的证据表明,脊髓刺激在治疗顽固性心绞痛、背部手术失败综合征和复杂区域疼痛综合征相关疼痛方面的疗效和成本效益。在这篇文章中,我们回顾了脊髓刺激的历史和病理生理学,以及在临床实践中有效的证据(或缺乏证据)。
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来源期刊
Mount Sinai Journal of Medicine
Mount Sinai Journal of Medicine 医学-医学:内科
自引率
0.00%
发文量
1
审稿时长
6-12 weeks
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