E Andersson, J Enander, P Andrén, E Hedman, B Ljótsson, T Hursti, J Bergström, V Kaldo, N Lindefors, G Andersson, C Rück
{"title":"Internet-based cognitive behaviour therapy for obsessive-compulsive disorder: a randomized controlled trial.","authors":"E Andersson, J Enander, P Andrén, E Hedman, B Ljótsson, T Hursti, J Bergström, V Kaldo, N Lindefors, G Andersson, C Rück","doi":"10.1017/S0033291712000244","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Cognitive behaviour therapy (CBT) is an effective treatment for obsessive-compulsive disorder (OCD) but access to CBT is limited. Internet-based CBT (ICBT) with therapist support is potentially a more accessible treatment. There are no randomized controlled trials testing ICBT for OCD. The aim of this study was to investigate the efficacy of ICBT for OCD in a randomized controlled trial.</p><p><strong>Method: </strong>Participants (n=101) diagnosed with OCD were randomized to either 10 weeks of ICBT or to an attention control condition, consisting of online supportive therapy. The primary outcome measure was the Yale-Brown Obsessive Compulsive Scale (YBOCS) administered by blinded assessors.</p><p><strong>Results: </strong>Both treatments lead to significant improvements in OCD symptoms, but ICBT resulted in larger improvements than the control condition on the YBOCS, with a significant between-group effect size (Cohen's d) of 1.12 (95% CI 0.69-1.53) at post-treatment. The proportion of participants showing clinically significant improvement was 60% (95% CI 46-72) in the ICBT group compared to 6% (95% CI 1-17) in the control condition. The results were sustained at follow-up.</p><p><strong>Conclusions: </strong>ICBT is an efficacious treatment for OCD that could substantially increase access to CBT for OCD patients. Replication studies are warranted.</p>","PeriodicalId":20891,"journal":{"name":"Psychological Medicine","volume":"42 10","pages":"2193-203"},"PeriodicalIF":5.9000,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1017/S0033291712000244","citationCount":"205","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Psychological Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1017/S0033291712000244","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2012/2/21 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"PSYCHIATRY","Score":null,"Total":0}
引用次数: 205
Abstract
Background: Cognitive behaviour therapy (CBT) is an effective treatment for obsessive-compulsive disorder (OCD) but access to CBT is limited. Internet-based CBT (ICBT) with therapist support is potentially a more accessible treatment. There are no randomized controlled trials testing ICBT for OCD. The aim of this study was to investigate the efficacy of ICBT for OCD in a randomized controlled trial.
Method: Participants (n=101) diagnosed with OCD were randomized to either 10 weeks of ICBT or to an attention control condition, consisting of online supportive therapy. The primary outcome measure was the Yale-Brown Obsessive Compulsive Scale (YBOCS) administered by blinded assessors.
Results: Both treatments lead to significant improvements in OCD symptoms, but ICBT resulted in larger improvements than the control condition on the YBOCS, with a significant between-group effect size (Cohen's d) of 1.12 (95% CI 0.69-1.53) at post-treatment. The proportion of participants showing clinically significant improvement was 60% (95% CI 46-72) in the ICBT group compared to 6% (95% CI 1-17) in the control condition. The results were sustained at follow-up.
Conclusions: ICBT is an efficacious treatment for OCD that could substantially increase access to CBT for OCD patients. Replication studies are warranted.
背景:认知行为疗法(CBT)是一种有效的治疗强迫症(OCD)的方法,但使用CBT的途径有限。在治疗师的支持下,基于网络的CBT (ICBT)可能是一种更容易获得的治疗方法。目前还没有随机对照试验测试ICBT治疗强迫症。本研究的目的是在一项随机对照试验中探讨ICBT治疗强迫症的疗效。方法:诊断为强迫症的参与者(n=101)被随机分配到10周的ICBT或注意控制条件,包括在线支持治疗。主要结果测量是由盲法评估者实施的耶鲁-布朗强迫症量表(YBOCS)。结果:两种治疗均显著改善了强迫症症状,但ICBT在YBOCS上的改善比对照组更大,治疗后组间效应量(Cohen’s d)为1.12 (95% CI 0.69-1.53)。ICBT组显示临床显著改善的参与者比例为60% (95% CI 46-72),而对照组为6% (95% CI 1-17)。结果在随访中得到维持。结论:ICBT是一种有效的治疗强迫症的方法,可以大大增加强迫症患者接受CBT的机会。重复研究是有必要的。
期刊介绍:
Now in its fifth decade of publication, Psychological Medicine is a leading international journal in the fields of psychiatry, related aspects of psychology and basic sciences. From 2014, there are 16 issues a year, each featuring original articles reporting key research being undertaken worldwide, together with shorter editorials by distinguished scholars and an important book review section. The journal''s success is clearly demonstrated by a consistently high impact factor.