Prognostic variables and surgical management of foot melanoma: review of a 25-year institutional experience.

ISRN Dermatology Pub Date : 2011-01-01 Epub Date: 2011-07-26 DOI:10.5402/2011/384729
Omar M Rashid, Julia C Schaum, Luke G Wolfe, Nooshin K Brinster, James P Neifeld
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引用次数: 14

Abstract

Introduction. Cutaneous foot melanoma is rare, challenging to manage, and not adequately examined in the literature. This study evaluated the prognostic variables and surgical management of foot melanoma. Materials and Methods. Foot melanoma cases managed at an academic center from 1985 to 2010 were retrospectively reviewed. Results. 46 patients were identified with a broad range of demographic characteristics. Overall recurrence was 32.6%: 19% acral lentiginous, 57% nodular, 66% superficial spreading, 30% melanoma unspecified, 50% severely atypical; 53% ulcerated, 23% nonulcerated; 29% on the dorsum of the foot, 17% heel, 60% ankle, 22% toe, 50% plantar; 0% <1 mm thick, 47% 1-4 mm, 33% >4 mm. 13 had positive nodes, 4 (31%) of whom recurred. Prognostic factors and recurrence did not correlate, and survival was 96% with a median followup of 91 months. Conclusions. Aggressive management of foot melanoma may result in excellent long-term survival even following disease recurrence.

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足部黑色素瘤的预后变量和手术治疗:回顾25年的机构经验。
介绍。皮肤足部黑色素瘤是罕见的,具有挑战性的管理,并没有充分检查的文献。本研究评估了足部黑色素瘤的预后变量和手术治疗。材料与方法。回顾性分析了1985年至2010年在某学术中心治疗的足部黑色素瘤病例。结果:46例患者具有广泛的人口统计学特征。总复发率为32.6%:19%肢端小晶状体,57%结节性,66%浅表扩散,30%不明黑色素瘤,50%严重不典型;53%溃疡,23%未溃疡;29%在脚背,17%在脚跟,60%在脚踝,22%在脚趾,50%在足底;0% 4毫米。阳性淋巴结13例,复发4例(31%)。预后因素与复发无相关性,生存率为96%,中位随访91个月。结论。积极管理足部黑色素瘤可能导致良好的长期生存,甚至在疾病复发后。
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