Prognostic factors in cutaneous squamous cell carcinoma: is patient delay in hospital visit a predictor of survival?

ISRN Dermatology Pub Date : 2011-01-01 Epub Date: 2011-11-14 DOI:10.5402/2011/285289
Y Endo, M Tanioka, Y Miyachi
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引用次数: 8

Abstract

The patient's delay in the visit to a hospital seems to play an important role in prognosis in invasive cutaneous squamous cell carcinoma (SCC). This report explored prognostic factors of cutaneous SCC focusing on patient delay in hospital visit. Data of 117 Japanese patients who were treated for invasive cutaneous SCC in our facility between 2000 and 2010 were used for analysis. A multivariate Cox proportional-hazard modelling revealed that a pair of TNM stage (hazard ratio, 5.0; 95% CI, 1.8 to 13.9) and poorer histological differentiation (hazard ratio, 3.2; 95% CI, 0.93 to 10.3), and a pair of tumour size (hazard ratio, 1.02; 95% CI, 1.004 to 1.04) and rapid growth (hazard ratio, 8.25; 95% CI, 1.29 to 52.7) were a prognostic factor whereas patient delay in hospital visit was not. However, patient delay in hospital visit was correlated with larger tumour size.

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皮肤鳞状细胞癌的预后因素:患者就诊延误是生存的预测因素吗?
在浸润性皮肤鳞状细胞癌(SCC)的预后中,患者的延迟就诊似乎起着重要的作用。本报告探讨了皮肤鳞状细胞癌的预后因素,重点是患者就诊延误。我们分析了2000年至2010年期间在我们医院接受侵袭性皮肤鳞状细胞癌治疗的117名日本患者的数据。多变量Cox比例风险模型显示,对TNM阶段(风险比,5.0;95% CI, 1.8 - 13.9)和较差的组织学分化(风险比,3.2;95% CI, 0.93 ~ 10.3)和肿瘤大小(风险比,1.02;95% CI, 1.004 ~ 1.04)和快速增长(风险比,8.25;95% CI(1.29 - 52.7)是影响预后的因素,而患者就诊延误则不是。然而,患者就诊延误与肿瘤大小有关。
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