Diagnostic efficacy of ultrasonography-guided fine needle aspiration biopsy in evaluating salivary gland malignancy.

Chang Gung medical journal Pub Date : 2012-01-01 DOI:10.4103/2319-4170.106165

Yu-Ting Huang, Shih-Ming Jung, Sheung-Fat Ko, Yao-Liang Chen, Siu-Cheung Chan, En-Haw Wu, Yi-Ming Wu, Yung-Liang Wan, Shu-Hang Ng

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引用次数: 13

Abstract

Background: Salivary gland masses constitute a diagnostic challenge in daily clinical practice and tissue sampling is required to establish a diagnosis. We aimed to evaluate the efficacy of ultrasonography-guided fine needle aspiration biopsy (UGFNAB) in the diagnosis of salivary gland lesions.

Methods: From January 2007 to September 2010, a total of 158 patients who underwent both UGFNAB and surgical excision for salivary gland mass lesions were included in this study. Patients with insufficient sampling or inconclusive cytology diagnosis were excluded from the analysis of diagnostic accuracy of UGFNAB.

Results: UGFNAB yielded sufficient sampling for analysis in 137 patients, leading to a diagnostic yield of 86.7%. Among these 137 patients, 24 patients were confirmed to have malignant tumors. The sensitivity, specificity and accuracy of UGFNAB for malignancy were 66.7%, 98.2%, and 92.7%, respectively. No UGFNAB-related complications were encountered.

Conclusions: UGFNAB of salivary gland masses is a safe technique that offers high specificity and accuracy but moderate diagnostic yield and sensitivity.

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超声引导下细针穿刺活检对涎腺恶性肿瘤的诊断价值。

背景:唾液腺肿块在日常临床实践中是一个诊断挑战，需要组织取样来建立诊断。目的探讨超声引导下细针穿刺活检(UGFNAB)在涎腺病变诊断中的应用价值。方法:2007年1月至2010年9月，共158例涎腺肿物病变同时行UGFNAB和手术切除的患者。取样不足或细胞学诊断不确定的患者被排除在UGFNAB诊断准确性分析之外。结果:UGFNAB为137例患者提供了足够的样本进行分析，诊断率为86.7%。在这137例患者中，有24例患者被确诊为恶性肿瘤。UGFNAB对恶性肿瘤的敏感性、特异性和准确性分别为66.7%、98.2%和92.7%。未见ugfna相关并发症。结论:UGFNAB检测唾液腺肿块是一种安全的技术，具有较高的特异性和准确性，但诊出率和敏感性适中。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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