Extramedical use of prescription pain relievers by youth aged 12 to 21 years in the United States: national estimates by age and by year.

Elizabeth A Meier, Jonathan P Troost, James C Anthony
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引用次数: 47

Abstract

OBJECTIVE To identify when youth are most likely to start using prescription pain relievers to get high or for other unapproved indications outside the boundaries of what a prescribing physician might intend (ie, extramedical use). DESIGN Cross-sectional surveys of adolescent cohorts, 2004 to 2008. SETTING The United States. PARTICIPANTS Large nationally representative samples of youth in the United States who had been assessed for the 2004 through 2008 National Survey on Drug Use and Health, yielding data from 138 729 participants aged 12 to 21 years. MAIN OUTCOME MEASURES Estimated age-specific risk of starting extramedical use of prescription pain relievers, year by year, and confirmation of age at peak risk by tracing the experience of individual cohorts during this period. RESULTS The estimated peak risk of starting extramedical use of prescription pain relievers occurs in midadolescence, well before the college years. The age at peak risk is 16 years, when an estimated 2% to 3% become newly incident users. Smaller risk estimates are observed at age 12 to 14 years and at age 19 to 21 years. CONCLUSIONS For initiatives to prevent youth from using prescription pain relievers to get high or for other unapproved indications, a focus on the last year of high school and the post-secondary school years may be too little too late. Practice-based approaches are needed in addition to public health interventions based on effective alcohol and tobacco prevention programs during the earlier adolescent years.

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美国12至21岁青少年处方止痛药的医疗外使用情况:按年龄和年份分列的国家估计。
目的:确定青少年最有可能在什么时候开始使用处方止痛药来获得快感或用于处方医生可能意图之外的其他未经批准的适应症(即医疗外使用)。设计2004 - 2008年青少年横断面调查。背景:美国。为2004年至2008年全国药物使用和健康调查评估的具有全国代表性的大量美国青年样本,获得了来自138729名12至21岁参与者的数据。主要结局指标:每年估计处方止痛药开始医疗外使用的年龄特异性风险,并通过追踪这一时期个体队列的经历来确认风险高峰年龄。结果:开始使用处方止痛药的最高风险发生在青春期中期,远早于大学时代。风险最高的年龄是16岁,估计有2%到3%的人成为新事件使用者。在12至14岁和19至21岁时观察到的风险估计较小。结论:为了防止青少年使用处方止痛药获得快感或其他未经批准的适应症,将重点放在高中最后一年和高中以上学年可能太少也太晚了。除了基于青少年早期有效的酒精和烟草预防规划的公共卫生干预措施之外,还需要基于实践的方法。
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