Computed tomography and pathological findings of five nasal neurilemmomas.

Jing Hu, Yang-Yang Bao, Ke-Jia Cheng, Shui-Hong Zhou, Ling-Xiang Ruan, Zhou-Jun Zheng
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引用次数: 25

Abstract

Objectives: Neurilemmomas are benign tumors deriving from Schwann cells of the nerve sheath. They occur in all parts of the body. The highest incidence of neurilemmoma is in the head and neck region (38-45%), but involvement of the nose and paranasal sinus is quite rare, with only sporadic cases having been reported in the world literature. Fewer than 4% of these tumors involve the nasal cavity and paranasal sinuses. We describe the clinical, pathologic, and computed tomography (CT) features of five nasal neurilemmomas.

Methodology: CT features of five patients with nasal schwannoma proved by operation and pathology were investigated.

Results: Schwannomas tend to be solitary and are usually well-circumscribed tumors with an oval, round or fusiform shape in the unilateral nasal cavity. The lesions usually have a mottled central lucency with peripheral intensification on contrast-enhanced CT scans. The heterogeneous appearance is related to areas of increased vascularity with adjacent non-enhancing cystic or necrotic regions.

Conclusions: Schwannoma should be considered in the differential of unusual nasal masses. Certain clinical and CT patterns may be of use in the differential diagnosis.

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5例鼻神经鞘瘤的ct及病理表现。
目的:神经鞘瘤是源自神经鞘雪旺细胞的良性肿瘤。它们出现在身体的各个部位。神经鞘瘤的发病率最高的是头颈部(38-45%),但累及鼻子和副鼻窦是相当罕见的,在世界文献中只有零星的病例报道。不到4%的肿瘤累及鼻腔和鼻窦。我们描述的临床,病理,和计算机断层扫描(CT)特征的五个鼻神经鞘瘤。方法:对5例经手术及病理证实的鼻神经鞘瘤的CT表现进行分析。结果:神经鞘瘤多发于单侧鼻腔,呈椭圆形、圆形或梭形。在CT增强扫描上病灶通常有斑驳的中央透光,周围增强。异质性表现与血管增强区与邻近无增强性的囊性或坏死区有关。结论:神经鞘瘤在鉴别鼻异常肿块时应予以考虑。某些临床和CT表现可用于鉴别诊断。
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