Gene delivery by functional inorganic nanocarriers.

Xian Jun Loh, Tung-Chun Lee
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引用次数: 13

Abstract

Gene delivery into cells to elicit cellular response has received a great attention recently. Viruses, lipids, peptides, cationic polymers and certain inorganic nanomaterials have been reported as gene delivery vectors. In this review, we focus on the recent literature on gene delivery using inorganic nanoparticles. This emerging field of study is concisely summarized and illustrated by selected examples and recent patents. New approaches and directions towards the practical use of multifunctional nanocarriers are highlighted.

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功能无机纳米载体的基因传递。
基因导入细胞引起细胞反应是近年来研究的热点。病毒、脂质、多肽、阳离子聚合物和某些无机纳米材料已被报道为基因传递载体。在这篇综述中,我们重点介绍了利用无机纳米颗粒进行基因传递的最新文献。这一新兴的研究领域通过选定的例子和最近的专利简明地总结和说明。强调了多功能纳米载体实际应用的新途径和新方向。
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