A DNA nanocapsule with aptamer-controlled open-closure function for targeted delivery.

Thomas Bentin
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引用次数: 5

Abstract

A DNA capsule fitted with aptamer controlled target sensing has been "woven" using a 7308-base single-stranded DNA "thread" and 196 staple oligonucleotides. The capsule enables logic-gated molecular cargo delivery to targeted cell surfaces.

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具有适体控制的靶向递送启闭功能的DNA纳米胶囊。
利用7308碱基单链DNA“线”和196个短链寡核苷酸“编织”出了一个具有适体控制靶标传感的DNA胶囊。胶囊使逻辑门控分子货物运送到目标细胞表面。
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